Automated Skin Cell Suspension Autograft Procedures

Question:

A provider at our facility has begun performing the new 2025 skin cell suspension autograft procedure. During this process, automated preparation of the autograft is performed, including enzymatic processing, disaggregation of skin cells, and filtration of harvested tissue. Currently, there is no specific CPT code that describes this work. Since we are advised to report an unlisted code for this service, what comparative CPT code would you recommend using to help determine appropriate reimbursement?

Answer:

For SCSA procedures using automated preparation devices, report the harvest codes (15011-15012) and application codes (15015-15018) based on the surface areas involved. Do not report the preparation codes 15013-15014 when automated devices are used, as these codes are exclusively reserved for manual mechanical disaggregation of skin cells.

According to CPT Assistant (December 2024, June 2025), the Skin Replacement Surgery subsection guidelines explicitly state that codes 15013-15014 "are not reported if the harvested skin is nonmanually processed (i.e., using automation)." When automation is used, only the physician's work in harvesting and application is separately reportable.

*This response is based on the best information available as of 11/06/25.