CPT 44130 “Separate Procedure” Designation

Question:

CPT 48150 describes a pancreatectomy, proximal subtotal with total duodenectomy, partial gastrectomy, choledochoenterostomy, and gastrojejunostomy, with pancreatojejunostomy. CPT 44130 describes an enteroenterostomy, an anastomosis of the intestine, with or without cutaneous enterostomy, and is designated by CPT as a “separate procedure.”

According to NCCI edits, there is a procedure-to-procedure (PTP) conflict between 44130 and 48150 when performed during the same encounter, which can be bypassed with modifier 59. If a provider routinely performs an enteroenterostomy in conjunction with the Whipple procedure to prevent future bile reflux—a common postoperative complication—is it appropriate to append modifier 59 to 44130?

Given that these procedures are frequently performed together, could the enteroenterostomy be considered an integral component of the Whipple procedure, rather than a distinct, independent, or unrelated service? While the Whipple procedure description does not specifically include an enteroenterostomy, it does involve bile redirection via choledochoenterostomy. The enteroenterostomy similarly aids in bile flow redirection, serving as an additional step to reduce bile reflux.

In light of this, should these procedures be routinely unbundled and billed together?

Answer:

While modifier 59 can technically be used to bypass the NCCI edit between CPT 44130 and CPT 48150, it is not generally appropriate to routinely unbundle and report these codes together.

According to Medicare NCCI guidelines and CPT principles regarding “separate procedures,” CPT 44130 should only be reported when it is performed independently or is clearly distinct from other procedures. In the context of a Whipple procedure (CPT 48150), the enteroenterostomy is typically considered an integral part of the overall surgical approach, especially when performed to prevent bile reflux—a known complication.

CPT 48150 is the Column 1 (comprehensive) code, and CPT 44130 is the Column 2 (component) code. The “separate procedure” designation for 44130 indicates that it should not be reported in conjunction with a more extensive procedure unless it is truly separate and unrelated.

Therefore, unless there is clear documentation that the enteroenterostomy was performed for a distinct reason unrelated to the Whipple procedure, routinely appending modifier 59 to report both codes together would not align with coding guidelines.

*This response is based on the best information available as of 11/20/25.